来自莱斯特大学的研究者们近日发表了一项研究，呼吁为南亚移民重新定义肥胖标准。
一组来自各所高校保健学和心血管部门的研究人员将该项研究的重点放在南亚移民重到何种程度，可以定义为肥胖。他们的研究已经发表在PLoS One杂志上。
近年来，南亚国家糖尿病和心脏病发病率持续增长，且得病年龄越来越小。这项研究显示，为南亚移民减小身体质量指数（BMI）和腰围标准以降低肥胖标准是亟待解决的。
Laura Gray博士和Kamlesh Khunti、Melanie Davies教授通过对来自莱斯特市的6000多名2型糖尿病患者进行调查研究得出数据。调查是由卫生部资助，而数据分析则是由NIHR CLAHRC – LNR协会负责的。NIHR CLAHRC – LNR集合了所有该区域顶尖的卫生保健方面的专家。
莱斯特大学教授Khunti说；“研究发现，我们以前定义的肥胖标准（BMI30 kg/m2）并不适用于南亚移民，而应该有所降低。这样做的目的是可以通过检测血糖、血压和胆固醇含量来及时采取相应措施以降低心血管疾病的发病风险。”
“我们建议，将南亚移民的肥胖标准定在BMI23-28 kg/m2之间，在此区间，糖尿病患病风险极高。”
研究者们还减小了腰围标准。
Khunti教授还表示；“这是我们第一次为移居英国的南亚移民重新定义肥胖标准，有很重要的临床意义。”（生物探索译）
相关英文论文摘要：
Defining Obesity Cut-Off Points for Migrant South Asians
Background
Body mass index (BMI) and waist circumference (WC) are used to define cardiovascular and type 2 diabetes risk. We aimed to derive appropriate BMI and WC obesity cut-off points in a migrant South Asian population.
Methods
4688 White Europeans and 1333 South Asians resident in the UK aged 40–75 years inclusive were screened for type 2 diabetes. Principal components analysis was used to derive a glycaemia, lipid, and a blood pressure factor. Regression models for each factor, adjusted for age and stratified by sex, were used to identify BMI and WC cut-off points in South Asians that correspond to those defined for White Europeans.
Findings
For South Asian males, derived BMI obesity cut-off points equivalent to 30.0 kg/m2 in White Europeans were 22.6 kg/m2 (95% Confidence Interval (95% CI) 20.7 kg/m2 to 24.5 kg/m2) for the glycaemia factor, 26.0 kg/m2 (95% CI 24.7 kg/m2 to 27.3 kg/m2) for the lipid factor, and 28.4 kg/m2 (95% CI 26.5 kg/m2 to 30.4 kg/m2) for the blood pressure factor. For WC, derived cut-off points for South Asian males equivalent to 102 cm in White Europeans were 83.8 cm (95% CI 79.3 cm to 88.2 cm) for the glycaemia factor, 91.4 cm (95% CI 86.9 cm to 95.8 cm) for the lipid factor, and 99.3 cm (95% CI 93.3 cm to 105.2 cm) for the blood pressure factor. Lower ethnicity cut-off points were seen for females for both BMI and WC.
Conclusions
Substantially lower obesity cut-off points are needed in South Asians to detect an equivalent level of dysglycemia and dyslipidemia as observed in White Europeans. South Asian ethnicity could be considered as a similar level of risk as obesity (in White Europeans) for the development of type 2 diabetes.
英文论文链：https://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0026464
