欧洲的研究人员在大鼠实验中证实，吃草莓能减少酒精对胃黏膜的损害。这项研究发表在公开访问期刊《PLoS ONE》，可能有助于改善胃溃疡的治疗。
草莓能保护胃免受酒精损伤
研究小组由意大利、塞尔维亚和西班牙的研究人员组成，他们证实在哺乳动物胃中草莓在酒精对胃的损害过程中具有保护作用。科学家向实验鼠灌注酒精，发现食用草莓后胃黏膜遭受较少的损害。
该研究的共同作者、巴塞罗那大学的研究者Sara Tulipani 解释道，草莓的正面作用不仅关系到草莓本身的抗氧化能力和高含量的酚类化合物，还涉及到它能激活机体酶和抗氧化防御机制。
研究结论指出，预防自由基或活性氧引起的胃病时，富含草莓的饮食能起到积极作用。这种水果能减缓人类胃溃疡的形成。
胃炎或胃黏膜炎的致病因素不仅包括酒精饮用，还包括病毒感染、非类固醇消炎药（如阿司匹林）和针对幽门螺杆菌的药物治疗。
马尔凯理工大学研究小组的协调员 Maurizio Battino 称，许多实验表明胃炎发病或治愈后，食用草莓能减轻胃损伤。
草莓减缓胃溃疡
连续十天（40毫克/每公斤每天）取食草莓提取物后，大鼠再被灌注酒精。研究人员发现它们的胃溃疡病情较轻。
Battino 强调，该研究的目的不是减轻醉酒，而是发现一类能保护胃黏膜免受不同溶剂损伤的分子。
目前，对胃溃疡和其它胃病的治疗需要新的保护性药物，它们具有抗氧化特性。草莓中的多种复合物很可能是新药的成分。（生物探索译）
相关英文论文摘要：
Strawberry Polyphenols Attenuate Ethanol-Induced Gastric Lesions in Rats by Activation
of Antioxidant Enzymes and Attenuation of MDA Increase.
BACKGROUND AND AIM: Free radicals are implicated in the aetiology of gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease. Strawberries are common and important fruit due to their high content of essential nutrient and beneficial phytochemicals which seem to have relevant biological activity on human health. In the present study we investigated the antioxidant and protective effects of three strawberry extracts against ethanol-induced gastric mucosa damage in an experimental in vivo model and to test whether strawberry extracts affect antioxidant enzyme activities in gastric mucosa.
METHODS/PRINCIPAL FINDINGS: Strawberry extracts were obtained from Adria, Sveva and Alba cultivars. Total antioxidant capacity and radical scavenging capacity were performed by TEAC, ORAC and electron paramagnetic resonance assays. Identification and quantification of anthocyanins was carried out by HPLC-DAD-MS analyses. Different groups of animals received 40 mg/day/kg body weight of strawberry crude extracts for 10 days. Gastric damage was induced by ethanol. The ulcer index was calculated together with the determination of catalase and SOD activities and MDA contents. Strawberry extracts are rich in anthocyanins and present important antioxidant capacity. Ethanol caused severe gastric damage and strawberry consumption protected against its deleterious role. Antioxidant enzyme activities increased significantly after strawberry extract intake and a concomitantly decrease in gastric lipid peroxidation was found. A significant correlation between total anthocyanin content and percent of inhibition of ulcer index was also found.
CONCLUSIONS: Strawberry extracts prevented exogenous ethanol-induced damage to rats' gastric mucosa. These effects seem to be associated with the antioxidant activity and phenolic content in the extract as well as with the capacity of promoting the action of antioxidant enzymes. A diet rich in strawberries might exert a beneficial effect in the prevention of gastric diseases related to generation of reactive oxygen species.
