英国医学期刊《柳叶刀》最近刊登一篇文章说，那些为了减肥而采用“缩胃”和“截肠”手术的人，术后会更易受酒精影响，只喝一点酒可能也容易醉，因此专家建议接受过这种手术的人哪怕只喝了一点酒也应避免开车。
“缩胃”和“截肠”手术被现在不少想减肥的人采用，它的正式名称是胃旁路术，简言之就是改变肠胃消化道的正常结构，使食物只经历部分胃和肠道，这样身体吸收的营养成分自然减少，帮助起到减肥效果。
但美国洛克菲勒大学的医学专家彼得•霍尔特在这篇文章中说，最近有案例显示，接受了这种手术的人哪怕只喝了一杯酒，在数小时后仍然检测出血液中的酒精含量超标。
他查阅相关资料后认为，这有多方面原因。首先，手术后被闲置在一旁的那部分肠胃中会积累一些细菌，它们会分解碳水化合物产生酒精，对有些曾接受手术者的检测显示，即使不喝酒血液中也含有微量酒精。第二，手术后身体对酒精的新陈代谢能力也会受到影响，在喝同样多酒的情况下，术后与术前相比血液中酒精浓度的峰值会更高，并且回落到正常水平的速度更慢。
霍尔特因此建议，接受过这种手术的人应该注意自身对酒精敏感度的变化，为了避免酒后驾车出现事故，他们哪怕只喝了一点酒也应避免开车。
生物探索推荐英文论文摘要：
I was recently made aware of a misadventure in a patient who had undergone Roux-en-Y gastric bypass several years previously. After a minor traffic accident in which the police were involved, the patient was given a breathalyser test for alcohol and, to his surprise, a level consistent with moderate intoxication was found. The patient admitted to drinking one glass of wine many hours previously. A review of published studies on alcohol metabolism after gastric bypass surgery indicates that such patients should be very concerned about elevated blood (and breath) alcohol concentrations out of proportion to intake.
For many years, it has been known that bacteria accumulating in stagnant loops of intestine can produce ethanol from ingested carbohydrate substrates. Small amounts of alcohol have been detected in the blood of patients after jejunoileal bypass surgery and in obese women. Bacterial accumulation can occur in the bypassed duodenal-jejunal loop in bypassed patients, potentially resulting in production of alcohols.
Furthermore, abnormal handling of small amounts of alcohol has been directly shown in a study of alcohol concentrations in breath before and 3 and 6 months after gastric bypass surgery for obesity. That study showed significantly elevated peak alcohol concentrations (reaching 0•08%) and a significant delay in the return of alcohol to baseline concentrations after drinking one glass of wine 6 months postoperatively.
Patients who have had gastric bypass have also reported greater sensitivity to small amounts of alcohol with more rapid intoxication and lower intolerance than before surgery.
Obesity surgery has become one of the commonest operations in western countries. These data mandate that patients undergoing Roux-en-Y gastric bypass surgery be warned that they could experience a major difference in their capacity to handle alcohol after their surgery and that they should consider not driving after drinking any alcohol at all.
全文阅读：
