Circulation:补充牛奶和大豆蛋白有助降血压

2011-07-22 09:54 · ada

美国的一项新研究成果显示,高血压患者补充牛奶蛋白和大豆蛋白有助于降低血压。

摘要:美国的一项新研究成果显示,高血压患者补充牛奶蛋白和大豆蛋白有助于降低血压。

美国杜兰大学公共卫生学院的研究人员7月18日在学术刊物《循环》(Circulation)的网络版上报告说,他们选取352名高血压患者,将其分成3组,分别每日服用40克牛奶蛋白补充剂、同样数量的大豆蛋白和碳水化合物补充剂。

连续服用8周后,研究人员发现,服用大豆蛋白补充剂的患者,其收缩压降低了2毫米汞柱,服用牛奶蛋白补充剂者的收缩压降低了2.3毫米汞柱。而服用碳水化合物补充剂的患者,其血压没有下降。

此前有研究发现,收缩压降低2毫米汞柱,意味着因中风致死的风险减少 6%,因心脏病致死的风险减少4%。美国目前有近7500万高血压患者,他们患心脏病、中风和肾损伤的风险较高。

 

生物探索推荐英文论文摘要:

Effect of Dietary Protein Supplementation on Blood Pressure

A Randomized, Controlled Trial

Abstract

Background—Observational studies have reported an inverse association between dietary protein intake and blood pressure (BP). We compared the effect of soy protein, milk protein, and carbohydrate supplementation on BP among healthy adults.

Methods and Results—We conducted a randomized, double-blind crossover trial with 3 intervention phases among 352 adults with prehypertension or stage 1 hypertension in New Orleans, LA, and Jackson, MS, from September 2003 to April 2008. The trial participants were assigned to take 40 g/d soy protein, milk protein, or carbohydrate supplementation each for 8 weeks in a random order. A 3-week washout period was implemented between the interventions. Three BPs were measured at 2 baseline and 2 termination visits during each of 3 intervention phases with a random-zero sphygmomanometer. Compared with carbohydrate controls, soy protein and milk protein supplementations were significantly associated with −2.0 mm Hg (95% confidence interval −3.2 to −0.7 mm Hg, P=0.002) and −2.3 mm Hg (−3.7 to −1.0 mm Hg, P=0.0007) net changes in systolic BP, respectively. Diastolic BP was also reduced, but this change did not reach statistical significance. There was no significant difference in the BP reductions achieved between soy or milk protein supplementation.

Conclusions—The results from this randomized, controlled trial indicate that both soy and milk protein intake reduce systolic BP compared with a high-glycemic-index refined carbohydrate among patients with prehypertension and stage 1 hypertension. Furthermore, these findings suggest that partially replacing carbohydrate with soy or milk protein might be an important component of nutrition intervention strategies for the prevention and treatment of hypertension.

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