摘要
目的：为确定孕妇的打鼾、睡眠姿势和其他的一些睡眠习惯与死胎的形成是否有关系
设计：病例对照研究所需的人口基数
地点：奥克兰，新西兰
实验对象：实验组是155名女性在2006.7——2009.6月有产下过妊娠28周以上非先天性畸形死胎的，控制组则是310名怀孕或妊娠期的女性。罗吉斯回归分析的多变量参数能够更好模拟已知复杂的因素 。
主要结果测量：孕妇打鼾，白天嗜睡度，入睡前和醒来后的睡姿（左右侧卧，俯卧，其他）
结果：研究结果死胎出生率是3.09:1000，孕妇打鼾或白天嗜睡度与死产之间并无关系。然而孕妇仰卧或右侧卧入睡比左侧卧孕妇更易出现死胎。孕妇睡姿是左侧卧的，死产儿概率是1.96/1000，而不是左侧卧睡姿的孕妇则为3.93/1000。夜里上厕所次数较少或不上厕所的女性比起床比较频繁的女性容易产下死胎。孕妇在妊娠的前几个月白天经常有睡眠习惯的也比没有白天睡眠习惯的孕妇容易产下死胎。
结论：这是首次报告死产与母亲睡眠习惯有关，这些研究结果需要进一步研究确认。（生物探索编译）
生物探索推荐英文论文摘要：
Association between maternal sleep practices and risk of late stillbirth: a case-control study
Abstract
Objectives To determine whether snoring, sleep position, and other sleep practices in pregnant women are associated with risk of late stillbirth.
Design Prospective population based case-control study.
Setting Auckland, New Zealand
Participants Cases: 155 women with a singleton late stillbirth (≥28 weeks’ gestation) without congenital abnormality born between July 2006 and June 2009 and booked to deliver in Auckland. Controls: 310 women with single ongoing pregnancies and gestation matched to that at which the stillbirth occurred. Multivariable logistic regression adjusted for known confounding factors.
Main outcome measure Maternal snoring, daytime sleepiness (measured with the Epworth sleepiness scale), and sleep position at the time of going to sleep and on waking (left side, right side, back, and other).
Results The prevalence of late stillbirth in this study was 3.09/1000 births. No relation was found between snoring or daytime sleepiness and risk of late stillbirth. However, women who slept on their back or on their right side on the previous night (before stillbirth or interview) were more likely to experience a late stillbirth compared with women who slept on their left side (adjusted odds ratio for back sleeping 2.54 (95% CI 1.04 to 6.18), and for right side sleeping 1.74 (0.98 to 3.01)). The absolute risk of late stillbirth for women who went to sleep on their left was 1.96/1000 and was 3.93/1000 for women who did not go to sleep on their left. Women who got up to go to the toilet once or less on the last night were more likely to experience a late stillbirth compared with women who got up more frequently (adjusted odds ratio 2.28 (1.40 to 3.71)). Women who regularly slept during the day in the previous month were also more likely to experience a late stillbirth than those who did not (2.04 (1.26 to 3.27)).
Conclusions This is the first study to report maternal sleep related practices as risk factors for stillbirth, and these findings require urgent confirmation in further studies.
