在线轻松预约,无需出国即可与美国医生“面对面”视频交流,获取权威专业的第二诊疗意见和方案!登录好医友官网查询更多美国医生信息(咨询热线4008860922)
【执业认证】
美国内科医学委员会——内科医师资格认证
美国内科医学委员会——肿瘤专科医师资格认证
美国内科医学委员会——血液专科医师资格认证
【医疗专长】
阿朗•辛格(Arun Singh)博士任职于远负盛名的加州大学洛杉矶分校罗纳德里根医学中心(Ronald Reagan UCLA Medical Center),在JCCC信号转导和治疗计划(JCCC Signal Transduction and Therapeutics Program Area)血液和肿瘤学分部担任资深临床研究员。他致力于为肉瘤病患研发新型治疗手段,深入研究促进癌细胞增长的机制和针对特定分支类型肉瘤的靶向疗法优化。在此过程中所得到的分析和结论转化为处于临床试验阶段I和阶段II的新型肉瘤药物,以满足临床药物开发的需要。在科研领域,阿朗•辛格博士发表大量的原创学术研究报告,被许多医学权威期刊杂志所收录。
【教育背景】
医学院校:毕业于新泽西医学院(New Jersey Medical School),获得医学博士学位;
实习/住院医培训:在哈佛医学院教学医院之一贝斯以色列女执事医疗中心(Beth Israel Deaconess Medical Center) 完成普通内科实习和住院医师训练;
专科培训:在加州大学洛杉矶分校医学院(UCLA, School of Medicine) 接受血液学和内科肿瘤学的专科临床培训。
【合作医院】
加州大学洛杉矶分校罗纳德里根医学中心(Ronald Reagan UCLA Medical Center)
加州大学洛杉矶分校圣塔莫尼卡医学中心(UCLA Medical Center-Santa Monica)
【临床试验】
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma(关于晚期或转移性软组织肉瘤患者联合使用Doxorubicin 和 Olaratumab的研究) Start of enrollment: 2015 Sep 01Acoba J.,Attia S.,Bailey H.,Boles S.,Carney J.,Chow W.,D'amato G.,Dang L.,Davis L.,Druta M.,Ganjoo K.,Hainsworth J.,Hartner L.,Inst. S.C.,Jahan T.,Keedy V.,Kendall S.,Kim E.,Leu K.,Maki R.,Okuno S.,Partri...
Adoptive Transfer of NY-ESO-1 TCR Engineered Peripheral Blood Mononuclear Cells (PBMC) After a Nonmyeloablative Conditioning Regimen, With Administration of NY-ESO-1157-165 Pulsed Dendritic Cells and Interleukin-2, in Patients With Advanced MalignanciesStart of enrollment: 2012 Nov 01Singh, A.S.
A Phase IB/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) (吉西他滨和多烯紫杉醇结合Pazopanib新辅助治疗软组织肉瘤的二期研究)(STS)Start of enrollment: 2011 Aug 01Schwartz, G.,Tap, W.
【出版物与演讲】PubMed
A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas.Munhoz, R. R.,D'Angelo, S. P.,Gounder, M. M.,Keohan, M. L.,Chi, P.,Carvajal, R. D.,Singer, S.,Crago, A. M.,Landa, J.,Healey, J. H.,Qin, L. X.,Hameed, M.,Ezeoke, M. O.,...; Oncologist. 2015 Oct 10.
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress.Austin, W. R., Armijo, A. L., Campbell, D. O., Singh, A. S., Hsieh, T., Nathanson, D., Herschman, H. R., Phelps, M. E., Witte, O. N., Czernin, J., Radu, C. G.; J Exp Med. 2012 Nov 19.
Evolution of gene auto-regulation in the presence of noise.Singh, A.,Hespanha, J. P.; IET Syst Biol. 2010 Oct 30.
Oncogenic and metastatic properties of preprotachykinin-I and neurokinin-1 genes.Singh, A.S., Caplan, A., Corcoran, K.E., Fernandez, J.S., Preziosi, M., Rameshwar, P.; Vascul Pharmacol. 2006 Oct.
In vivo models of prostate cancer metastasis to bone.Singh, A.S., Figg, W.D.; J Urol. 2005 Sep.
Mechanisms of disease: Polymorphisms of androgen regulatory genes in the development of prostate cancer.Singh, A.S., Chau, C.H., Price, D.K., Figg, W.D.; Nat Clin Pract Urol. 2005 Feb.
Genotyping and functional analysis of the D104N variant of human endostatin.Macpherson, G.R., Singh, A.S., Bennett, C.L., Venzon, D.J., Liewehr, D.J., Franks, M.E., Dahut, W.L., Kantoff, P.W., Price, D.K., Figg, W.D.; Cancer Biol Ther. 2004 Dec.
Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.Paoluzzi, L., Singh, A.S., Price, D.K., Danesi, R., Mathijssen, R.J., Verweij, J., Figg, W.D., Sparreboom, A.; J Clin Pharmacol. 2004 Aug.
【新闻报道】
2014年Dr. Arun Singh explains approved treatments for GIST Patients
2015年Dr. Arun Singh on an Early-Stage Trial of Immunotherapy for Advanced Sarcomas
2016年9月 美国商业新闻社(Business Wire)
【擅长治疗】
Adenosarcoma腺肉瘤
Adamantinoma of Bone 骨釉质瘤
Alveolar soft part sarcoma腺泡状软组织肉瘤
Angioleiomyoma血管平滑肌瘤
Angiomatoid fibrous histiocytoma血管瘤样的纤维性组织细胞瘤
Angiomyolipoma血管肌脂肪瘤
Angiomyxoma血管粘液瘤
Angiosarcoma血管肉瘤
Atypical Fibroxanthoma非典型纤维黄色瘤
Atypical lipomatous tumor非典型脂肪瘤肿瘤
Bone cancer骨癌
Carcinosarcoma癌肉瘤
Chondroblastoma成软骨细胞瘤
Chondromyxoid Fibroma软骨粘液样纤维瘤
Chondrosarcoma软骨肉瘤
Chordoma脊索瘤
CIC-DUX4 associated tumor CIC-DUX4相关的肿瘤
Clear cell sarcoma (malignant melanoma of soft parts) 透明细胞肉瘤
Deep Leiomyoma深部平滑肌瘤
Dermatofibrosarcoma protuberans (DFSP) 隆突性皮肤纤维肉瘤
Desmoid tumor韧带样瘤
Desmoplastic Fibroma of Bone骨促结缔组织增生性纤维瘤
Desmoplastic small round cell tumors多小圆细胞肿瘤
Elastofibroma弹力纤维瘤
Endometrial stromal sarcoma子宫内膜间质肉瘤
Epithelioid Hemangioma上皮样血管瘤
Epithelioid sarcoma上皮样肉瘤
Ewing’s sarcoma尤文氏肉瘤
Extrarenal rhabdoid tumor肾外横纹肌样瘤
Extraskeletal mesenchymal chondrosarcoma骨外间叶性软骨肉瘤
Extraskeletal myxoid chondrosarcoma骨外黏液样软骨肉瘤
Extraskeletal osteosarcoma骨外骨肉瘤
Fibromatosis纤维瘤病
Fibromyxoid sarcoma纤维黏液肉瘤
Fibrous Dysplasia骨纤维结构发育不良
Fibrous histiocytoma of bone骨纤维组织细胞瘤
Fibrosarcoma纤维肉瘤
Follicular Dendritic Cell sarcoma滤泡树突状细胞肉瘤
Gastrointestinal stromal tumor (GIST) 胃肠道间质瘤
Giant Cell Tumor of Bone骨巨细胞瘤
Giant Cell Tumor of Soft Tissue软组织巨细胞瘤
Granulation cell Sarcoma颗粒细胞肉瘤
Hemangioendothelioma血管内皮瘤
Hemangioma血管瘤
Hemangiopericytoma血管外皮细胞瘤
Hibernoma蛰伏脂瘤
High Grade Sarcoma高级别肉瘤
Hodgkins Lymphoma of Bone骨霍奇金淋巴瘤
Inflammatory myofibroblastic tumor炎症性肌纤维母细胞瘤
Intimal sarcoma内膜肉瘤
Kaposi sarcoma 卡波西肉瘤
Langerhans Histiocytosis朗格汉斯组织细胞增生症
Leiomyosarcoma平滑肌肉瘤
Lipoma脂肪瘤
Lipoblastoma成脂细胞瘤
Liposarcoma脂肪肉瘤
Malignant fibrous histiocytoma (MFH) 恶性纤维组织细胞瘤
Malignant glomus tumor恶性血管球瘤
Malignant granular cell tumor恶性颗粒细胞瘤
Malignant mesenchymoma恶性间叶瘤
Malignant peripheral nerve sheath tumor (MPNST) 恶性外周神经鞘膜瘤
Multiple Hereditary exostoses of bone遗传性多发外生骨疣
Myelolipoma髓脂肪瘤
Myoepithelioma/mixed tumor of soft tissue软组织肌上皮瘤/混合瘤
Myofibroblastic sarcoma肌纤维母细胞肉瘤
Myxofibrosarcoma黏液纤维肉瘤
Myxoid Liposarcoma黏液样脂肪肉瘤
Myxoma粘液瘤
Neurofibroma纤维神经瘤
Neurofibrosarcoma神经纤维肉瘤
Osteoblastoma成骨细胞瘤
Osteofibrous Dysplasia骨纤维结构不良
Osteosarcoma骨肉瘤
Paget’s Disease佩吉特氏病
PEComa血管周上皮样细胞肿瘤
Phosphaturic Mesenchymal Tumor (Mesenchymal Phosphaturic Tumor) 磷酸盐尿性间叶肿瘤
Phyllodes Tumor, Malignant恶性叶状瘤
Pigmented Villonodular Synovitis (PVNS) 绒毛结节性滑膜
Plasmacytoma浆细胞瘤
Primitive Neuroectodermal Tumor(PNET) 原始神经外胚层肿瘤
Radiation associated sarcomas辐射相关肉瘤
Rhabdomyosarcoma横纹肌肉瘤
Schwannoma神经鞘瘤
Soft tissue sarcoma软组织肉瘤
Solitary fibrous tumor孤立性纤维瘤
Spindle cell sarcoma梭细胞肉瘤
Synovial Chondromatosis滑膜性软骨瘤病
Synovial sarcoma滑膜肉瘤
Undifferentiated Epithelioid Sarcoma未分化的上皮样肉瘤
Undifferentiated pleomorphic sarcoma未分化多形性肉瘤
Undifferentiated Round Cell Sarcoma未分化细胞肉瘤
Undifferentiated Sarcoma未分化肉瘤
Undifferentiated Spindle Cell Sarcoma未分化的梭形细胞肉瘤
Uterine Leiomyosarcoma子宫肉瘤
附图: