摘要:基因表达的调控是一个最基本的生理过程,控制细胞增殖、分化和生理功能。近来,基因组图谱的技术改进和生物信息学的分析有助于在表观基因组和的转录调控上实现突破,并且更好地应用于技术领域和实验结果分析。
表观基因组折叠方式
The regulation of gene expression represents one of the most fundamental of biologic processes that controls cellular proliferation, differentiation, and function. Recent technological advances in genome-wide annotation together with bioinformatic/computational analyses have contributed significantly to our understanding of transcriptional regulation at the epigenomic and regulomic levels. This perspective outlines the techniques that are being utilized and summarizes a few of the outcomes. ? 2011 American Society for Bone and Mineral Research.
全文网站:https://onlinelibrary.wiley.com/doi/10.1002/jbmr.317/abstract;jsessionid=A204ACE1DCF3B1E0E5F94F618F8A0332.d01t04