2013研究前沿:生命科学与医学最新热点方向排名

2013-05-17 13:20 · wenmingw

汤森路透首次发布了前沿研究、科研管理与科学政策制定的相关报告:《2013研究前沿:科学与社科领域的百强研究》。报告中列出了当前十大前沿研究领域,以及每个领域中排名前十的重点研究。这次公布的研究,也可能成为2013年度科学与社科领域的重点。

日前,汤森路透首次发布了前沿研究、科研管理与科学政策制定的相关报告:《2013研究前沿:科学与社科领域的百强研究》(Research Fronts 2013: 100 Top Ranked Specialties in the Sciences and Social Sciences)。报告中列出了当前十大前沿研究领域,以及每个领域中排名前十的重点研究。这次公布的研究,也可能成为2013年度科学与社科领域的重点。

该报告对2007年至2012年高引用率的研究论文,以及发表在核心期刊和基础期刊上的文章进行分析后发现,科学与社会科学领域的前沿研究主要涉及以下十大领域:

农业、植物与动物科学(Agriculture, Plant and Animal Sciences)

生态学与环境科学(Ecology and Environmental Sciences)

地球科学(Geosciences)

临床医学(Clinical Medicine)

生物科学(Biological Sciences)

化学与材料科学(Chemistry and Materials Science)

物理学(Physics)

天文学与天体物理学(Astronomy and Astrophysics)

数学、计算科学与工程学(Mathematics, Computer Science and Engineering)

经济学、心理学和其他社会科学(Economics, Psychology and Other Social Sciences)

研究人员表示,对科研领域进行趋势分析能让研究人员、科研资助者和机构管理人员对当前的科研发展有一个整体认识,帮助他们在科研精力投入、科研资金和资源分配等方面做出更好的决策。

生物科学(Biological Sciences)领域中排名前十的重点研究如下:

RANKresearch frontscore
papers
citationsmean year of
core papers
1DNA methylation analysis and missing heritability253,1532011
2Toxicity of amyloid beta (Aβ) oligomers in Alzheimer’s disease452,5882010.6
3Differentiation and function of follicular helper CD4 T cells (TFH)3827602010.5
4Human beta(2) adrenergic G-protein-coupled receptors (GPCRs)4462612010.4
5Linear ubiquitin chain assembly complex and activation of nuclear factor-κB (NF-κB)433,7492010.4
6Lgr5 receptor-expressing intestinal stem cells232,6992010.3
7TET mutations, reduction of 5-hydroxymethylcytosine (5hmC), and malignancy456,1122010.2
8Inhibition of TO R (Target Of Rapamycin) signaling, increased lifespan, and diseases of aging303,1522010.1
9HIV-1 Vpu and Vpx proteins and restriction factors SAMHD1 and BST -2/Tetherin483,7602009.9
10Mitochondrial sirtuins and regulation of metabolism323,3952009.9

位列三甲的分别为: DNA甲基化与丢失遗传性研究、阿尔茨海默症的β淀粉样蛋白(Aβ)、滤泡辅助性CD4 T细胞(TFH)的分化和功能。

农业、植物与动物科学(Agriculture, Plant and Animal Sciences)领域中排名前十的重点研究如下:

RANKresearch frontscore
papers
citationsmean year of
core papers
1Impact of climate change on food crops3215372010
2Comprehensive classification of fungi based on molecular evolutionary analysis1813742010
3Arabidopsis chloroplast RnA editing4625782009.9
4Jasmonate biosynthesis and signaling3325482009.9
5oomycete RXlR effectors and suppression of plant immunity4723402009.7
6Angiosperm phylogeny group classification3422592009.7
7methicillin-resistant Staphylococcus aureus (mRsA) in livestock1710712009.7
8genomic selection and estimated breeding values3922812009.6
9honey bee colony collapse disorder and Nosema ceranae3017182009.6
10insect resistance to transgenic crops producing bt (Bacillus thuringiensis) toxins for pest control2211342009.6

生态学与环境科学(Ecology and Environmental Sciences)领域中排名前十的重点研究如下:

RANKresearch frontscore
papers
citationsmean year of
core papers
1ocean acidification and marine ecosystems4536532009.6
2biodiversity and functional ecosystems4331392009.5
3mangrove forests and climate change1611212009.5
4models and impacts of land-use change1823182009.4
5biochar amendment techniques and effects4123002009.4
6Adaptive evolution in invasive species and approximate bayesian computation1912552009.4
7Chytridiomycosis and large-scale amphibian population extinctions1310032009.3
8Pharmaceutical residues in environmental water and wastewater5038152009.1
9Community ecology and phylogenetic comparative biology201,7992009.1
10limate warming, altered thermal niches, and species impact141,2442009.1

临床医学(Clinical Medicine)领域中排名前十的重点研究如下:

RANKresearch frontscore
papers
citationsmean year of
core papers
1transcatheter aortic valve implantation5028182011
2Atypical hemolytic uremic syndrome and complement activation3619392010.6
3Acquired bRAf inhibitor resistance in metastatic melanoma3647772010.5
4idiopathic pulmonary fibrosis and randomized placebo-controlled drug trials3822692010.5
5Pathology and treatment of nonalcoholic fatty liver disease3419782010.5
6Chemotherapy with and without bevacizumab for heR2-negative breast cancer1419092010.5
7brentuximab vedotin for refractory and relapsed hodgkin’s lymphoma2320012010.4
8il28b polymorphisms and treatment response in hepatitis C patients4751722010.3
9Anaplastic lymphoma kinase (AlK) inhibition in non-small cell lung cancer4637162010.3
10global, national, and regional assessments of maternal, newborn, and child health4226402010.3